Open minds. Big Brother host Julie Chen got emotional on the Wednesday, June 17, episode of The Talk while discussing the first transgender houseguest to ever appear on the series in the upcoming 17th season.

"You're going to see something that you've never seen before in the Big Brother house," Chen, 45, explained to her fellow co-hosts. "That saying holds true for me and the rest of the Big Brother staff." The CBS personality then told the audience about the transgender woman named Audrey Middleton — who was confirmed as a cast member to Us Weekly on Tuesday — and played her introductory reel.